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CGP 3466B maleate

CAS No. 200189-97-5

CGP 3466B maleate ( Omigapil (Maleate); Omigapil maleate )

产品货号. M27464 CAS No. 200189-97-5

Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥365 有现货
5MG ¥591 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CGP 3466B maleate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
  • 产品描述
    Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).(In Vivo):Treatment with Omigapil (0.1 mg/kg) in 12-week-old dyW/ mag mice results in improved muscle regeneration and increased force .
  • 同义词
    Omigapil (Maleate); Omigapil maleate
  • 通路
    Apoptosis
  • 靶点
    Apoptosis
  • 受体
    Bacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    200189-97-5
  • 分子量
    391.4
  • 分子式
    C23H21NO5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C(=C\C(O)=O)\C(O)=O.C(N(CC#C)C)C=1C=2C(OC=3C(C1)=CC=CC3)=CC=CC2
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Ríos F, et al. Anaerobic digestion of amine-oxide-based surfactants: biodegradation kinetics and inhibitory effects. Biodegradation. 2017 Aug;28(4):303-312.
产品手册
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